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Collapsing airway pathologies, such as vanishing bronchus syndrome, are routinely treated by airway stent implantation. Off-the-shelf stents are appropriate for the treatment of most patients. However, in some cases, these commercially available stents do not fit the patient's airway anatomy sufficient, resulting in a high risk for dislocation and infection. In this article, we present a process for design and manufacturing of patient-specific tracheobronchial stents that allows treatment of patients in whom standard treatment is not appropriate.