Transactions on Additive Manufacturing Meets Medicine
Vol. 3 No. 1 (2021): Trans. AMMM
https://doi.org/10.18416/AMMM.2021.2109521

Material Properties, Structural Designs, and Printing Technologies, ID 521

Bioactivity assessment of additively manufactured doped-HA composite scaffolds for bone tissue engineering

Main Article Content

Swati Jindal (Nanotechnology and Integrated Bio‐Engineering Centre (NIBEC) , Ulster University, UK), Cecile Serenelli (Nanotechnology and Integrated Bio‐Engineering Centre (NIBEC) , Ulster University, UK), Elena Mancuso (Nanotechnology and Integrated Bio‐Engineering Centre (NIBEC) , Ulster University, UK)

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Abstract

Composites are promising candidates for treating bone defects, but manufacturing of composite scaffolds is challenging. This study aimed to fabricate composite scaffolds based on polycaprolactone (PCL) and doped Hydroxyapatite (HA) via a single step melt extrusion additive manufacturing technique. Starting from the raw powder forms, the printed scaffolds were produced and then characterized for morphology, mechanical behavior and in vitro mineralization. MicroCT revealed the homogenous dispersion of ceramic particles in the PCL matrix. Also, SEM showed the ceramic particles on the surfaces of printed scaffolds. Furthermore, bioactivity assays confirmed the enhanced apatite deposit formation on composite scaffolds compared to PCL alone.

Article Details

How to Cite

Jindal, S., Serenelli, C. ., & Mancuso, E. (2021). Bioactivity assessment of additively manufactured doped-HA composite scaffolds for bone tissue engineering. Transactions on Additive Manufacturing Meets Medicine, 3(1), 521. https://doi.org/10.18416/AMMM.2021.2109521