Transactions on Additive Manufacturing Meets Medicine
Vol. 2 No. 1 (2020): Trans. AMMM
https://doi.org/10.18416/AMMM.2020.2009022

Scaffolds, Implants and Drug Delivery Systems

Strategies to evaluate alginate based bioinks applying extrusion printing for biofabrication

Main Article Content

Emine Karakya (Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Erlangen, Germany), Lena Fischer (Biophysics Group, Department of Physics, University of Erlangen-Nuremberg, Erlangen, Germany), Jonas Hazur (Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Erlangen, Germany), Aldo R. Boccaccini (Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Erlangen, Germany), Ingo Thievessen (Biophysics Group, Department of Physics, University of Erlangen-Nuremberg, Erlangen, Germany), Rainer Detsch (Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Erlangen, Germany)

Copyright (c) 2020 AMMM

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Abstract

For bioprinting, tailored bioinks combining tissue-like mechanical properties, printability and high biocompatibility are needed. The strategy of this project includes the precise characterization of the synthesis route and material properties, description of the printing process, as well as computing of flow and shear stress profile inside the printing needle. Furthermore, in vitro analyses using lentiviral fluorescent reporter cells were performed, which is a novel method that has so far hardly been used in biofabrication. The evaluation of the hydrogel and printing process for successful biofabrication is a multi-stage process and in our case demonstrated that ADA-GEL is a promising bioink.

Article Details

How to Cite

Karakya, E. ., Fischer, L., Hazur, J., Boccaccini, A. R. ., Thievessen, I., & Detsch, R. (2020). Strategies to evaluate alginate based bioinks applying extrusion printing for biofabrication. Transactions on Additive Manufacturing Meets Medicine, 2(1). https://doi.org/10.18416/AMMM.2020.2009022