Transactions on Additive Manufacturing Meets Medicine
Vol 2 No 1 (2020): Trans. AMMM
https://doi.org/10.18416/AMMM.2020.2009021

Scaffolds, Implants and Drug Delivery Systems

PEGDA drug delivery scaffolds manufactured with a novel hybrid AM process

Main Article Content

Rekowska Natalia (University Medical Centre Rostock), Niels Grabow (University Medical Center Rostock), Hermann Seitz (University of Rostock), Robert Mau (University of Rostock), Alexander Reiss (University of Rostock), Jan Konasch (University of Rostock), Thomas Eickner (University Medical Center Rostock), Michael Teske (University Medical Center Rostock)

Abstract

Additive manufacturing (AM) of drug delivery systems (DDS) is a promising tool for the development of patient-tailored treatments to ensure exact formation of individual scaffolds with specific incorporated drug combinations and concentrations. This study describes a novel hybrid AM process, combining stereolithography and inkjet printing, for printing a basic Polyethylene Glycol Diacrylate (PEGDA) DDS body and placing the model drug acetylsalicylic acid (ASA) in different drug depot locations. Adjusting the drug release by drug depot positioning according to drug diffusion is being investigated. The drug release rates from first 3D printed samples are being shown. 

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