Transactions on Additive Manufacturing Meets Medicine
Vol 1 No 1 (2019): Trans. AMMM
https://doi.org/10.18416/AMMM.2019.1909S03P17

Scaffolds, Implants and Drug Delivery Systems

Integration of subtractive 3D printing into micromolding of biodegradable implants for spinal cord treatment

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Jana Marina von Poblotzki (Technical University of Hamburg), Hoc Khiem Trieu (Technical University of Hamburg)

Abstract

Spinal cord injury (SCI) is a life-changing event potentially leading to permanent paralysis. We developed a mechanical microconnector system (mMS) to promote regeneration after SCI. The new micromolding of the mMS starts with a premaster build from a subtractive 3D printing method called selective laser induced etching (SLE). We additionally could facilitate molding of the silicone master through a monolayer coating of Trichloro(1H, 1H, 2H, 2H-perfluorooctyl)silane (FOTS) and Dimethyldichlorosilane (DDMS). This technology enables us to build complex biodegradable implant structures in a range from 25 micrometers up to several millimeters.

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