Transactions on Additive Manufacturing Meets Medicine
Vol 1 No 1 (2019): Trans. AMMM
https://doi.org/10.18416/AMMM.2019.1909S03P14

Scaffolds, Implants and Drug Delivery Systems

Hot Melt Extrusion and 3D-Printing of different PVA-Qualities

Main Article Content

Julius Krause (Department of Biopharmaceutics and Pharmaceutical Technology, University of Greifswald, Germany), Linus Großmann (Department of Biopharmaceutics and Pharmaceutical Technology, University of Greifswald, Germany), Werner Weitschies (Department of Biopharmaceutics and Pharmaceutical Technology, University of Greifswald, Germany)

Abstract

3D printing of oral dosage forms offers a possibility to individualize the dose. This paper examines the suitability of different PVA qualities for 3D printing. By using Hot Melt Extrusion it was possible to produce filaments containing the active substances which could be printed into tablets. The drug release profile can be influenced depending on the PVA quality used and the infill of the tablets.

Article Details