Transactions on Additive Manufacturing Meets Medicine
Vol 1 No 1 (2019): Trans. AMMM
https://doi.org/10.18416/AMMM.2019.1909S12T02

Medical Phantoms for Planning, Training, and Quality Assurance

Additive manufacturing: A growing platform to replace, reduce and refine animal experiments

Main Article Content

E. Unger (Center for Medical physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria), M. E. Schweda (Department / Department of Small Animals and Horses, Veterinary University Vienna, Austria), A. M. Kramer (Department of Biomedical Research, Medical University of Vienna, Austria), M. P. Schaffarich (Department of Biomedical Research, Medical University of Vienna, Austria), F. Moscato (Center for Medical physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria), G. Oberoi (Center for Medical physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria)

Abstract

Replacement, Reduction and Refinement (3Rs) are the bedrock of animal experiments and additive manufacturing (AM) fortifies these principles. To evaluate the accuracy of 3D models, we built skeletal models of rabbit head, based on Micro-Magnetic Radiation Imaging (uMRI) and Micro-Computed Tomography (uCT). Data was segmented using a computer software and the reconstructed stereolithography file was printed in 1:1 scaled model using a polyjet printer. Point-based part comparison analysis (PCA) was performed to gauge its dimensional accuracy. The results displayed that AM-workflow is an accurate process for reproducing life size skeletal models, however support material cleaning requires further research.


 

Article Details