Transactions on Additive Manufacturing Meets Medicine
Vol 1 No 1 (2019): Trans. AMMM
https://doi.org/10.18416/AMMM.2019.1909S09T03

Scaffolds, Implants and Drug Delivery Systems

3D-printed PEGDA structure with multiple depots for advanced drug delivery systems

Main Article Content

Jan Konasch (Chair of Microfluidics, University of Rostock, Rostock, Germany), Alexander Riess (Chair of Microfluidics, University of Rostock, Rostock, Germany), Robert Mau (Chair of Microfluidics, University of Rostock, Rostock, Germany), Michael Teske (Institute for Biomedical Engineering, University Medical Center Rostock, Germany), Natalia Rekowska (Institute for Biomedical Engineering, University Medical Center Rostock, Germany), Thomas Eickner (Institute for Biomedical Engineering, University Medical Center Rostock, Germany), Niels Grabow (Institute for Biomedical Engineering, University Medical Center Rostock, Germany), Hermann Seitz (Chair of Microfluidics, University of Rostock, Rostock, Germany and Department Life, Light & Matter, University of Rostock, Germany)

Abstract

Additive manufacturing technologies have the potential to make an important contribution to the field of personalized medicine. Besides customized implants, drug delivery systems (DDS) should be tailored to the patient’s specific needs. We developed a hybrid additive manufacturing system based on stereolithography and inkjet printing to generate DDS with selectively incorporated depots of active pharmaceutical ingredients (API) to tailor the release kinetics of the API. In this work we report on the successful proof-of-principle of 3D printing of PEGDA specimens containing depots with two different inks.

Article Details